NUR-550 – Translational Research and Population Health Management Course

Translational Research and Population Health Management

Course Code Type Duration Credit Hours

NUR-550 v:11 Credit Based 56 Days 4.0 .1

Course Description
In this course, students examine the process of scientific inquiry, knowledge generation, utilization, and dissemination of evidence into advanced nursing practice in order to propose quality improvement initiatives that advance the delivery of safe, high-quality care for patient populations. Students critically evaluate evidence, including scientific findings from the biopsychosocial fields, epidemiology, biostatistics, genetics, and genomics, and apply levels of evidence and theoretical frameworks to design culturally appropriate clinical prevention interventions and population-based care that reduce risks, prevent disease, and promote health and well-being. Students also consider strategies to evaluate health policy and advocacy issues, the state of health care delivery, patient-centered care, and ethical principles related to health beliefs, health promotion, and risk reduction for diverse populations. Students apply these strategies to work towards recognizing gaps in nursing and health care knowledge, identifying potential solutions or innovations for those gaps, planning and implementing practice changes, and evaluating the outcomes in order to improve practice. Prerequisite: NUR-513.

Pre-Requisites
NUR-513.
Co-Requisites
NUR-550
Course Materials
Nash, D. B., Fabius, R. J., Skoufalos, A., Clarke, J. L., & Horowitz, M. R. (2016). Population health: Creating a culture of wellness. Burlington, MA: Jones & Bartlett Learning. ISBN-13: 9781284047929

Advanced Nursing Research: From Theory to Practice

Description:
Tappan, R. M. (2016). Advanced nursing research: From theory to practice (2nd ed.). Burlington, MA: Jones & Bartlett Learning. ISBN-13: 9781284048308

Evidence-Based Practice in Nursing and Healthcare

Description:
Melnyk, B. M., & Fineout-Overholt, E. (2015). Evidence-based practice in nursing and healthcare (3rd ed.). Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins. ISBN-13: 9781451190946

NUR-550 Course Objectives
Description:
In this course, the student will:

Explore research articles, nursing and related theories, applying levels of evidence, and theoretical frameworks to identify quality research studies.
Demonstrate understanding of scientific inquiry, knowledge generation, utilization, and dissemination in advanced nursing practice.
Evaluate the evidence for potential solutions/innovations that can potentially solve a health care issue and improve patient outcomes.
Identify gaps in nursing knowledge and EBP that can potentially be resolved by planning and implementing a practice change project.
Formulate a clinically researchable question amenable to an innovative evidence-based practice change
Write a scholarly literature review that supports a clinically researchable question amenable to an innovative evidence-based practice change proposal.
Evaluate health policy and advocacy issues for the purpose of improving health care outcomes.
Engage in scientific inquiry into the state of health care delivery, patient-centered care, and ethical principles related to health beliefs, health promotion, and risk reduction of diverse populations.
Propose quality improvement initiatives that advance the delivery of safe, high-quality health care.
Use principles from epidemiology, biostatistics, genetics, genomics, and cultural competence to guide comparisons of various patient populations.
Topic 1: Quality Research and Theoretical Frameworks
Description
Objectives:

Differentiate translational research from evidence-based
Discuss the application of translational research to population health
Discuss models of translational
Evaluate sources of translational
Study Materials
Advanced Practice Nursing: Essential Knowledge for the Profession

Description:
Read Chapter 22 in Advanced Practice Nursing: Essential Knowledge for the Profession.

Advanced Nursing Research: From Theory to Practice

Description:
Read Chapters 1-3 and 25 in Advanced Nursing Research: From Theory to Practice.

Evidence-Based Practice in Nursing and Healthcare

Description:
Read Chapter 1 in Evidence-Based Practice in Nursing and Healthcare.

Translational Research: A Historical Overview and Contemporary Reflections on the Transformative Nature of Research

Description:
Read “Translational Research: A Historical Overview and Contemporary Reflections on the Transformative Nature of Research,” by Boynton and Elster, from Journal of Research Administration (2012).

Practice-Based Research Priorities for Palliative Care: Results From a Research-to-Practice Consensus Workshop

Description:
Read “Practice-Based Research Priorities for Palliative Care: Results From a Research-to-Practice Consensus Workshop,” by Pillemer, Chen, Riffin, Prigerson, Schultz, and Reid, from American Journal of Public Health (2015).

Translational Research and Nursing Science

Description:
Read “Translational Research and Nursing Science,” by Grady, from Nursing Outlook (2010).

GCU Library: Nursing and Health Sciences Research Guide

Description:
Review the “Nursing and Health Sciences” research guide, located on the GCU Library website.

Translational Research Graphic Organizer Template

Description:
Use the “Translational Research Graphic Organizer Template” to complete the Topic 1 assignment.

Tasks
Topic 2: Research Framework and Legal and Ethical Translation
Description
Objectives:

Discuss ethical guidelines for conducting translational
Examine ethical and legal considerations related to translating research into
Discuss ethical research considerations specific to population
Study Materials
Tasks
Topic 3: Methodology and Data
Description
Objectives:

Differentiate types of translational research
Compare the validity of translational research to traditional research and data collection
Describe strategies to maintain the integrity of translational
Discuss challenges of research design and data collections related to population
Study Materials
Tasks
Topic 4: Epidemiology, Biostatistics, Genetics, and Genomics
Description
Objectives:

Describe the role of epidemiology in researching and addressing population health
Discuss the value of biostatistics in population health
Connect ecological, global, and social determinants of health and principles of genetics, genomics, and epidemiology to translational
Study Materials
Advanced Practice Nursing: Essential Knowledge for the Profession

Description:
Review Chapter 20 in Advanced Practice Nursing: Essential Knowledge for the Profession.

Population Health: Creating a Culture of Wellness

Description:
Read Chapters 2-4 in Population Health: Creating a Culture of Wellness.

Advanced Nursing Research: From Theory to Practice

Description:
Read Chapter 7 in Advanced Nursing Research: From Theory to Practice.

The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact

Description:
Read “The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact,” by Khoury, Gwinn, and Ioannidis, from American Journal of Epidemiology(2010).

Beyond Base Pairs to Bedside: a Population Perspective on How Genomics Can Improve Health

Description:
Read “Beyond Base Pairs to Bedside: A Population Perspective on How Genomics Can Improve Health,” by Khoury, Gwinn, Bowen, and Dotson, fromAmerican Journal of Public Health (2012).

Translational Research in Genomics of Alzheimer’s Disease: A Review of Current Practice and Future Perspectives

Description:
Read “Translational Research in Genomics of Alzheimer’s Disease: A Review of Current Practice and Future Perspectives,” by Mihaescu, Detmar, Cornel, van der Flier, Heutink, Hol, Rikkert, van Duijn, and Janssens, from Journal of Alzheimer’s Disease (2010).

Personalizing Health Care: Feasibility and Future Implications

Description:
Read “Personalizing Health Care: Feasibility and Future Implications,” by Godman, Finlayson, Cheema,

Zebedin-Brandl, Gutiérrez-Ibarluzea, Jones, Malmström, Asola, Baumgärtel, Bennie, Bishop, Bucsics, Campbell, Diogene, Ferrario, Fürst, Garuoliene, Gomes, Harris, and Haycox, from BMC Medicine (2013).

Tasks
PICOT (Population/Problem, Intervention, Comparison, Outcome, and Time to achieve the outcome) is a method that helps clarify the qualities needed to create a good question out of a practice issue or problem affecting the population of focus. Additionally, the information derived from a good PICOT makes it easier to perform a literature search in order to find translational research sources that can be used to address the clinical problem.

Use a national, state or local population health care database to research indicators of disparity. Choose a mortality/morbidity indicator to identify a clinical problem or issue that you want to explore pertaining to a population of focus. Use this indicator to begin to formulate a PICOT and conduct research on the population.

Write a 750-1,000-word paper that analyzes your research and focuses on the population you have chosen. Describe the population’s demographics and health concerns, and explain how nursing science, health determinants, and epidemiologic, genomic, and genetic data may impact population health management for the selected population. Provide an overview of a potential solution for solving the health issue related to your population and the intended PICOT statement. Describe how the solution incorporates health policies and goals that support health care equity for the population of focus.

You are required to cite three to five sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

Benchmark Information

This benchmark assignment assesses the following programmatic competencies: MS Nursing: Public Health

MS Nursing: Education

MS Nursing: Acute Care Nurse Practitioner MS Nursing: Family Nurse Practitioner

MS Nursing: Health Care Quality and Patient Safety

:Synthesize nursing science, determinants of health, and epidemiologic, genomic, and genetic data in the management of population health.
Topic 4 DQ 1
Description:
How does epidemiology helps in researching and addressing population health challenges? Provide a specific contemporary example.

Topic 4 DQ 2
Description:
Research a health concern that impacts a population with which you are familiar. How do biostatistics affect the research focus? How do you define the population as your patient? Make sure to include the population and health concern.

Week 4 Participation
Description:

Topic 5: Evidence for Improving Safety and Quality and Barriers to Translation
Description
Objectives:

Explain how translational research can be used for safety and quality improvement initiatives related to improving population
Discuss common barriers for translating research into
Study Materials
Tasks
Topic 6: Quality Improvement Initiatives and Clinical Prevention Interventions
Description
Objectives:

Evaluate quality improvement initiatives related to improving population health
Evaluate clinical prevention interventions that promote health and wellness for
Study Materials
Tasks
Use the GCU Library to perform a search for peer-reviewed research articles. Find five peer-reviewed primary source translational research articles.

In a paper of 1,250-1,500 words, synthesize the research into a literature review. The literature review should provide an overview for the reader that illustrates the research related to your particular PICOT. Include the following:

Introduction: Describe the clinical issue or problem you are
Methods: Describe the criteria you used in choosing your articles
Synthesize the Literature: Part A: Discuss the main components of each article (subjects, methods, key findings) and provide rationale for how this supports your PICOT; Part B: Compare and contrast the articles: Discuss limitations, controversies, and similarities/differences of the
Areas of Further Study: Analyze the evidence presented in your articles to identify what is known, unknown, and requires further
You are required to cite five to 10 sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

Benchmark Information
This benchmark assignment assesses the following programmatic competencies: MS Nursing: Public Health

MS Nursing: Education

MS Nursing: Acute Care Nurse Practitioner MS Nursing: Family Nurse Practitioner

MS Nursing: Health Care Quality and Patient Safety

: Analyze appropriate research from databases and other information sources to improve health care practices and processes.
Topic 6 DQ 1
Description:
Identify a quality improvement initiative that relates to improving population health outcomes for a population with which you are familiar. Have these initiatives been successful? Why or why not?

Topic 6 DQ 2
Description:
Identify a clinical prevention intervention to promote health and wellness for a population with which you are familiar. Have these clinical prevention interventions been successful? Why or why not?

Week 6 Participation
Description:
Topic 7: Policies Affecting Practice and State of Health Care Delivery
Description
Objectives:

Identify major policy issues affecting the state of health care delivery and population health
Analyze the components of effective population-based health
Discuss the impact of population health policies and initiatives on advanced nursing
Study Materials
Tasks
Topic 8: Using Research to Support Health Policy, Advocacy and Policy Development
Description
Objectives:

Discuss the role of translational research in advancing equitable access to health care and prevention services and policies based on population
Evaluate the role of the advanced practice nurse in advocating for equitable population health services and
Study Materials
Tasks

Benchmark – Population Health Policy Analysis
Description:
Select a current or proposed health care policy that is designed to improve a specific population’s access to quality, cost-effective health care. In a paper of 1,000-1,250 words, include the following:

Explain the policy and how it is designed to improve cost-effectiveness and health care equity for the population. Is the policy financially sound? Why or why not? How does the policy account for any relevant ethical, legal, and political factors and the nursing perceptive one must consider when implementing it?
To what state, federal, global health policies or goals is this particular policy related? How well do you think the policy is designed to achieve those goals?
Finally, discuss the advocacy strategies you would employ on behalf of your population to ensure they have access to the benefits of the Explain, from a Christian perspective, the professional and moral obligation of advanced registered nurse to advocate for and promote health and prevent disease among diverse populations.
You are required to cite five to 10 sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

Benchmark Information
This benchmark assignment assesses the following programmatic competencies: MS Nursing: Public Health

MS Nursing: Education

MS Nursing: Acute Care Nurse Practitioner MS Nursing: Family Nurse Practitioner

MS Nursing: Health Care Quality and Patient Safety

: Examine financially sound health care policy that incorporates the nursing perspective and relevant ethical, legal, and political factors.
: Determine advocacy strategies for improving access, quality, and cost-effective health care for diverse
: Integrate appropriate state, federal, and global health policies and goals into the design of equitable health care for populations.
: Examine the professional and moral obligation of master’s-prepared nurses to respect human dignity and advance the common good through working to promote health and prevent disease among diverse populations from a Christian perspective.
Topic 8 DQ 1
Description:
Define how translational research plays a role in influencing policy? Provide an example of a local health care policy that has been recently enacted and or is awaiting legislative passage that has been influenced by research.

Grade Scale
Final Grade Column

Letter Grade GPA Value Minimum (%) Maximum (%)
A 4.0 97.0 100.0
A- 3.7 93.0 96.99
B+ 3.3 89.0 92.99
B 3.0 85.0 88.99
B- 2.7 81.0 84.99
C+ 2.3 78.0 80.99
C 2.0 76.0 77.99
F 0.0 0.02 75.99
I 0.0 0.0 0.01
Grade Categories

Assignments (%) Points Percentile
Benchmark – Part B: Literature Review 250.0 —
Benchmark – Population Health Policy Analysis 160.0 —
Translational Research Graphic Organizer 100.0 —
Benchmark – Part A: Population Health Research and PICOT Statement
250.0

Discussion Question (%) Points Percentile
Topic 6 DQ 1 5.0 —
Topic 5 DQ 1 5.0 —
Topic 1 DQ 1 5.0 —
Topic 7 DQ 2 5.0 —
Topic 1 DQ 2 5.0 —
Topic 5 DQ 2 5.0 —
Topic 3 DQ 2 5.0 —
Topic 8 DQ 2 5.0 —
Topic 2 DQ 1 5.0 —
Topic 6 DQ 2 5.0 —
Topic 4 DQ 1 5.0 —
Topic 8 DQ 1 5.0 —
Topic 3 DQ 1 5.0 —
Topic 7 DQ 1 5.0 —
Topic 2 DQ 2 5.0 —
Topic 4 DQ 2 5.0 —

Participation (%) Points Percentile
Week 3 Participation 20.0 —

Participation (%) Points Percentile
Week 4 Participation 20.0 —

Participation (%) Points Percentile
Week 2 Participation 20.0 —

Participation (%) Points Percentile
Week 7 Participation 20.0 —

Participation (%) Points Percentile
Week 8 Participation 20.0 —

Participation (%) Points Percentile
Week 6 Participation 20.0 —

Participation (%) Points Percentile

Week 5 Participation 20.0 —

Participation (%) Points Percentile
Week 1 Participation 20.0 —

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